MLB scores: Wednesday, May 21, 2025

• Cincinnati Reds at Pittsburgh Pirates final score and box score
  CINCincinnati Reds1
  PITPittsburgh Pirates3

  Final · PNC Park · MLB.TV, FanDuel SN OH

• Chicago Cubs at Miami Marlins final score and box score
  CHCChicago Cubs2
  MIAMiami Marlins1

  Final · loanDepot park · FanDuel SN FL

• Houston Astros at Tampa Bay Rays final score and box score
  HOUHouston Astros4
  TBTampa Bay Rays8

  Final · George M. Steinbrenner Field · FanDuel SN Sun

• Baltimore Orioles at Milwaukee Brewers final score and box score
  BALBaltimore Orioles8
  MILMilwaukee Brewers4

  Final · American Family Field · MAS+, MASN2, MLB.TV

• Detroit Tigers at St. Louis Cardinals final score and box score
  DETDetroit Tigers5
  STLSt. Louis Cardinals1

  Final · Busch Stadium · FanDuel SN DET, MLB.TV

• Seattle Mariners at Chicago White Sox final score and box score
  SEASeattle Mariners6
  CHWChicago White Sox5

  Final · Rate Field · MLB.TV, Root Sports NW

• Kansas City Royals at San Francisco Giants final score and box score
  KCKansas City Royals8
  SFSan Francisco Giants4

  Final · Oracle Park · FanDuel SN KC, MLB.TV

• Cleveland Guardians at Minnesota Twins final score and box score
  CLECleveland Guardians5
  MINMinnesota Twins1

  Final · Target Field · MLB.TV, CLEGuardians.TV

• Atlanta Braves at Washington Nationals
  ATLAtlanta Braves0
  WSHWashington Nationals0

  6:45 PM · Nationals Park · MASN, MLBN

• New York Mets at Boston Red Sox final score and box score
  NYMNew York Mets5
  BOSBoston Red Sox1

  Final · Fenway Park · MLB Net

• Texas Rangers at New York Yankees final score and box score
  TEXTexas Rangers3
  NYYNew York Yankees4

  Final · Yankee Stadium · Prime Video

• San Diego Padres at Toronto Blue Jays final score and box score
  SDSan Diego Padres0
  TORToronto Blue Jays14

  Final · Rogers Centre · Sportsnet One

• Philadelphia Phillies at Colorado Rockies final score and box score
  PHIPhiladelphia Phillies9
  COLColorado Rockies5

  Final · Coors Field · MLB.TV, NBC Sports Phil

• Los Angeles Angels at Athletics final score and box score
  LAALos Angeles Angels10
  ATHAthletics5

  Final · Sutter Health Park · FanDuel SN West, MLB.TV

• Arizona Diamondbacks at Los Angeles Dodgers final score and box score
  ARIArizona Diamondbacks1
  LADLos Angeles Dodgers3

  Final · Dodger Stadium · MLB.TV, DBACKS.TV