Minnesota Twins players with 500+ career HR
3 players
3 players with 500+ career HR played for the Minnesota Twins. They are Jim Thome, Harmon Killebrew, and David Ortiz.
| Player | Pos | With club | Career |
|---|---|---|---|
| Jim Thome | DH | 2010–2011 | 612 |
| Harmon Killebrew | — | 1954–1974 | 573 |
| David Ortiz | DH | 1997–2002 | 541 |
The career total counts wherever it was made, as the Immaculate Grid counts it: one season with the club is enough. Every season since 1876 is on file. A season split between two clubs is filed as one combined line and counts for neither.