| Yogi BerraNew York Yankees | 10 | 1947–1962 | 2,150 |
| Joe DiMaggioNew York Yankees | 9 | 1936–1951 | 2,214 |
| Phil RizzutoNew York Yankees | 8 | 1941–1956 | 1,588 |
| Frankie CrosettiNew York Yankees | 8 | 1932–1947 | 1,541 |
| Bill DickeyNew York Yankees | 8 | 1928–1943 | 1,969 |
| Lou GehrigNew York Yankees | 8 | 1923–1939 | 2,721 |
| Mickey MantleNew York Yankees | 7 | 1951–1962 | 2,415 |
| Hank BauerNew York Yankees | 7 | 1949–1958 | 1,424 |
| Tommy HenrichNew York Yankees | 7 | 1937–1950 | 1,297 |
| Johnny MurphyNew York Yankees | 7 | 1932–1943 | — |
| Babe RuthBoston Red Sox, New York Yankees | 7 | 1915–1932 | 2,873 |
| Herb PennockBoston Red Sox, New York Yankees, Philadelphia Athletics | 7 | 1913–1932 | — |
| Bob CervNew York Yankees | 6 | 1951–1962 | 624 |
| Whitey FordNew York Yankees | 6 | 1950–1962 | — |
| Charlie SilveraNew York Yankees | 6 | 1949–1956 | 136 |
| Jerry ColemanNew York Yankees | 6 | 1949–1956 | 558 |
| Joe CollinsNew York Yankees | 6 | 1949–1956 | 596 |
| Tommy ByrneNew York Yankees | 6 | 1943–1956 | — |
| Allie ReynoldsNew York Yankees | 6 | 1947–1953 | — |
| Ralph HoukNew York Yankees | 6 | 1947–1953 | 43 |
| Vic RaschiNew York Yankees | 6 | 1947–1953 | — |
| Charlie KellerNew York Yankees | 6 | 1939–1952 | 1,085 |
| Spud ChandlerNew York Yankees | 6 | 1937–1947 | — |
| Lefty GomezNew York Yankees | 6 | 1932–1941 | — |
| Red RuffingNew York Yankees | 6 | 1932–1941 | — |
| Eddie CollinsChicago White Sox, Philadelphia Athletics | 6 | 1910–1930 | 3,315 |
| Andy PettitteNew York Yankees | 5 | 1996–2009 | — |
| Derek JeterNew York Yankees | 5 | 1996–2009 | 3,465 |
| Jorge PosadaNew York Yankees | 5 | 1996–2009 | 1,664 |
| Mariano RiveraNew York Yankees | 5 | 1996–2009 | — |
| Ramiro MendozaBoston Red Sox, New York Yankees | 5 | 1996–2004 | — |
| David ConeNew York Yankees, Toronto Blue Jays | 5 | 1992–2000 | — |
| Luis SojoNew York Yankees, Toronto Blue Jays | 5 | 1993–2000 | 671 |
| Paul O'NeillCincinnati Reds, New York Yankees | 5 | 1990–2000 | 2,105 |
| Catfish HunterNew York Yankees, Oakland Athletics | 5 | 1972–1978 | — |
| Ken HoltzmanNew York Yankees, Oakland Athletics | 5 | 1972–1978 | — |
| Reggie JacksonNew York Yankees, Oakland Athletics | 5 | 1972–1978 | 2,584 |
| Dal MaxvillOakland Athletics, St. Louis Cardinals | 5 | 1964–1974 | 748 |
| Bill SkowronLos Angeles Dodgers, New York Yankees | 5 | 1956–1963 | 1,566 |
| Gil McDougaldNew York Yankees | 5 | 1951–1958 | 1,291 |
| Billy MartinNew York Yankees | 5 | 1950–1956 | 877 |
| Ed LopatNew York Yankees | 5 | 1949–1953 | — |
| Gene WoodlingNew York Yankees | 5 | 1949–1953 | 1,585 |
| Johnny MizeNew York Yankees | 5 | 1949–1953 | 2,011 |
| Bobby BrownNew York Yankees | 5 | 1947–1952 | 452 |
| Johnny HoppNew York Yankees, St. Louis Cardinals | 5 | 1942–1952 | 1,262 |
| Billy JohnsonNew York Yankees | 5 | 1943–1951 | 882 |
| Johnny LindellNew York Yankees | 5 | 1941–1950 | — |
| Joe GordonCleveland Indians, New York Yankees | 5 | 1938–1948 | 1,530 |
| George SelkirkNew York Yankees | 5 | 1936–1941 | 810 |
| Red RolfeNew York Yankees | 5 | 1936–1941 | 1,394 |
| Art JorgensNew York Yankees | 5 | 1932–1939 | 176 |
| Tony LazzeriNew York Yankees | 5 | 1927–1937 | 1,840 |
| Stuffy McInnisBoston Red Sox, Philadelphia Athletics, Pittsburgh Pirates | 5 | 1910–1925 | 2,405 |
| Jack BarryBoston Red Sox, Philadelphia Athletics | 5 | 1910–1916 | 1,009 |