Chicago White Sox vs St. Louis Cardinals head-to-head
Who has won more, the Chicago White Sox or the St. Louis Cardinals?
St. Louis Cardinals lead the series 28-19 in 47 meetings since Sep 1, 1997. They average 4.6 to 5.1. The last meeting was Sep 13, 2026, 3-1.
- Record
- Chicago White Sox 19-28 St. Louis Cardinals
- Games
- 47
- Points per game
- 4.6 – 5.1
- Biggest win
- Chicago White Sox by 14
Every meeting on file
| Sep 13, 2026 |  CHW at  STL | 1-3 | St. Louis Cardinals | Regular |
| Sep 12, 2026 | CHW at STL | 6-5 | Chicago White Sox | Regular |
| Sep 11, 2026 | CHW at STL | 3-7 | St. Louis Cardinals | Regular |
| Jun 19, 2025 | STL at CHW | 5-4 | St. Louis Cardinals | Regular |
| Jun 19, 2025 | STL at CHW | 8-6 | St. Louis Cardinals | Regular |
| Jun 17, 2025 | STL at CHW | 12-2 | St. Louis Cardinals | Regular |
| May 5, 2024 | CHW at STL | 5-1 | Chicago White Sox | Regular |
| May 4, 2024 | CHW at STL | 6-5 | Chicago White Sox | Regular |
| May 3, 2024 | CHW at STL | 0-3 | St. Louis Cardinals | Regular |
| Jul 9, 2023 | STL at CHW | 4-3 | St. Louis Cardinals | Regular |
| Jul 8, 2023 | STL at CHW | 3-0 | St. Louis Cardinals | Regular |
| Jul 7, 2023 | STL at CHW | 7-8 | Chicago White Sox | Regular |
| May 26, 2021 | STL at CHW | 4-0 | St. Louis Cardinals | Regular |
| May 25, 2021 | STL at CHW | 3-8 | Chicago White Sox | Regular |
| May 24, 2021 | STL at CHW | 1-5 | Chicago White Sox | Regular |
| Aug 16, 2020 | STL at CHW | 2-7 | Chicago White Sox | Regular |
| Aug 15, 2020 | STL at CHW | 5-1 | St. Louis Cardinals | Regular |
| Aug 15, 2020 | STL at CHW | 6-3 | St. Louis Cardinals | Regular |
| Jul 11, 2018 | STL at CHW | 0-4 | Chicago White Sox | Regular |
| Jul 10, 2018 | STL at CHW | 14-2 | St. Louis Cardinals | Regular |
| May 2, 2018 | CHW at STL | 2-3 | St. Louis Cardinals | Regular |
| May 1, 2018 | CHW at STL | 2-3 | St. Louis Cardinals | Regular |
| Jul 22, 2015 | STL at CHW | 3-2 | St. Louis Cardinals | Regular |
| Jul 21, 2015 | STL at CHW | 8-5 | St. Louis Cardinals | Regular |
| Jul 1, 2015 | CHW at STL | 7-1 | Chicago White Sox | Regular |
| Jun 30, 2015 | CHW at STL | 2-1 | Chicago White Sox | Regular |
| Jun 14, 2012 | CHW at STL | 3-5 | St. Louis Cardinals | Regular |
| Jun 13, 2012 | CHW at STL | 0-1 | St. Louis Cardinals | Regular |
| Jun 12, 2012 | CHW at STL | 6-1 | Chicago White Sox | Regular |
| Jun 22, 2006 | STL at CHW | 0-1 | Chicago White Sox | Regular |
| Jun 21, 2006 | STL at CHW | 5-13 | Chicago White Sox | Regular |
| Jun 20, 2006 | STL at CHW | 6-20 | Chicago White Sox | Regular |
| Jun 17, 2001 | CHW at STL | 3-8 | St. Louis Cardinals | Regular |
| Jun 16, 2001 | CHW at STL | 3-8 | St. Louis Cardinals | Regular |
| Jun 15, 2001 | CHW at STL | 3-10 | St. Louis Cardinals | Regular |
| Jul 15, 2000 | STL at CHW | 7-15 | Chicago White Sox | Regular |
| Jul 14, 2000 | STL at CHW | 9-4 | St. Louis Cardinals | Regular |
| Jul 13, 2000 | STL at CHW | 13-5 | St. Louis Cardinals | Regular |
| Jul 17, 1999 | CHW at STL | 6-8 | St. Louis Cardinals | Regular |
| Jul 16, 1999 | CHW at STL | 9-8 | Chicago White Sox | Regular |
| Jul 15, 1999 | CHW at STL | 2-3 | St. Louis Cardinals | Regular |
| Jun 10, 1998 | STL at CHW | 8-10 | Chicago White Sox | Regular |
| Jun 9, 1998 | STL at CHW | 5-4 | St. Louis Cardinals | Regular |
| Jun 8, 1998 | STL at CHW | 6-8 | Chicago White Sox | Regular |
| Sep 3, 1997 | CHW at STL | 2-4 | St. Louis Cardinals | Regular |
| Sep 2, 1997 | CHW at STL | 1-6 | St. Louis Cardinals | Regular |
| Sep 1, 1997 | CHW at STL | 5-4 | Chicago White Sox | Regular |
Completed games on file, which start in 1997 — not the clubs’ full all-time series. Regular season 47, postseason 0.