Chicago White Sox vs San Francisco Giants head-to-head
Who has won more, the Chicago White Sox or the San Francisco Giants?
San Francisco Giants lead the series 40-35 in 78 meetings since Mar 7, 2000. They average 5.0 to 5.5. The last meeting was May 24, 2026, 8-5.
- Record
- Chicago White Sox 35-40-3 San Francisco Giants
- Games
- 78
- Points per game
- 5.0 – 5.5
- Biggest win
- Chicago White Sox by 12
San Francisco Giants have won the last 2 meetings.
Every meeting on file
| May 24, 2026 |  CHW at  SF | 5-8 | San Francisco Giants | Regular |
| May 23, 2026 | CHW at SF | 3-10 | San Francisco Giants | Regular |
| May 22, 2026 | CHW at SF | 9-4 | Chicago White Sox | Regular |
| Mar 12, 2026 | CHW at SF | 3-3 | Chicago White Sox | Preseason |
| Mar 2, 2026 | SF at CHW | 6-5 | San Francisco Giants | Preseason |
| Jun 29, 2025 | SF at CHW | 2-5 | Chicago White Sox | Regular |
| Jun 28, 2025 | SF at CHW | 0-1 | Chicago White Sox | Regular |
| Jun 27, 2025 | SF at CHW | 3-1 | San Francisco Giants | Regular |
| Mar 17, 2025 | SF at CHW | 3-0 | San Francisco Giants | Preseason |
| Mar 6, 2025 | CHW at SF | 3-7 | San Francisco Giants | Preseason |
| Aug 21, 2024 | CHW at SF | 6-2 | Chicago White Sox | Regular |
| Aug 20, 2024 | CHW at SF | 1-4 | San Francisco Giants | Regular |
| Aug 19, 2024 | CHW at SF | 3-5 | San Francisco Giants | Regular |
| Mar 16, 2024 | SF at CHW | 11-7 | San Francisco Giants | Preseason |
| Mar 10, 2024 | CHW at SF | 4-5 | San Francisco Giants | Preseason |
| Apr 6, 2023 | SF at CHW | 16-6 | San Francisco Giants | Regular |
| Apr 5, 2023 | SF at CHW | 3-7 | Chicago White Sox | Regular |
| Apr 3, 2023 | SF at CHW | 12-3 | San Francisco Giants | Regular |
| Mar 23, 2023 | SF at CHW | 6-3 | San Francisco Giants | Preseason |
| Jul 3, 2022 | CHW at SF | 13-4 | Chicago White Sox | Regular |
| Jul 2, 2022 | CHW at SF | 5-3 | Chicago White Sox | Regular |
| Jul 1, 2022 | CHW at SF | 1-0 | Chicago White Sox | Regular |
| Mar 24, 2022 | SF at CHW | 9-6 | San Francisco Giants | Preseason |
| Mar 22, 2021 | SF at CHW | 2-7 | Chicago White Sox | Preseason |
| Mar 4, 2021 | CHW at SF | 1-3 | San Francisco Giants | Preseason |
| Mar 7, 2020 | CHW at SF | 7-12 | San Francisco Giants | Preseason |
| Feb 25, 2020 | SF at CHW | 3-4 | Chicago White Sox | Preseason |
| Mar 18, 2019 | SF at CHW | 5-2 | San Francisco Giants | Preseason |
| Feb 25, 2019 | CHW at SF | 4-4 | Chicago White Sox | Preseason |
| Sep 10, 2017 | SF at CHW | 1-8 | Chicago White Sox | Regular |
| Sep 9, 2017 | SF at CHW | 1-13 | Chicago White Sox | Regular |
| Sep 8, 2017 | SF at CHW | 9-2 | San Francisco Giants | Regular |
| Mar 26, 2017 | SF at CHW | 3-4 | Chicago White Sox | Preseason |
| Mar 20, 2017 | SF at CHW | 3-2 | San Francisco Giants | Preseason |
| Mar 2, 2017 | CHW at SF | 8-6 | Chicago White Sox | Preseason |
| Mar 27, 2016 | CHW at SF | 13-9 | Chicago White Sox | Preseason |
| Mar 22, 2016 | SF at CHW | 7-8 | Chicago White Sox | Preseason |
| Mar 12, 2015 | SF at CHW | 7-4 | San Francisco Giants | Preseason |
| Aug 13, 2014 | CHW at SF | 1-7 | San Francisco Giants | Regular |
| Aug 12, 2014 | CHW at SF | 3-2 | Chicago White Sox | Regular |
| Jun 18, 2014 | SF at CHW | 6-7 | Chicago White Sox | Regular |
| Jun 17, 2014 | SF at CHW | 2-8 | Chicago White Sox | Regular |
| Mar 22, 2014 | SF at CHW | 8-5 | San Francisco Giants | Preseason |
| Mar 12, 2014 | CHW at SF | 3-4 | San Francisco Giants | Preseason |
| Mar 4, 2013 | SF at CHW | 2-6 | Chicago White Sox | Preseason |
| Feb 25, 2013 | CHW at SF | 9-9 | Chicago White Sox | Preseason |
| Mar 25, 2012 | SF at CHW | 2-5 | Chicago White Sox | Preseason |
| Mar 16, 2011 | SF at CHW | 5-3 | San Francisco Giants | Preseason |
| Mar 9, 2011 | CHW at SF | 2-4 | San Francisco Giants | Preseason |
| Mar 23, 2010 | SF at CHW | 6-1 | San Francisco Giants | Preseason |
| Mar 9, 2010 | CHW at SF | 2-6 | San Francisco Giants | Preseason |
| Mar 20, 2009 | SF at CHW | 10-3 | San Francisco Giants | Preseason |
| Mar 19, 2009 | CHW at SF | 4-6 | San Francisco Giants | Preseason |
| May 18, 2008 | CHW at SF | 13-8 | Chicago White Sox | Regular |
| May 17, 2008 | CHW at SF | 3-1 | Chicago White Sox | Regular |
| May 16, 2008 | CHW at SF | 2-0 | Chicago White Sox | Regular |
| Mar 21, 2008 | CHW at SF | 3-4 | San Francisco Giants | Preseason |
| Mar 8, 2008 | SF at CHW | 4-6 | Chicago White Sox | Preseason |
| Mar 26, 2007 | CHW at SF | 2-3 | San Francisco Giants | Preseason |
| Mar 21, 2007 | SF at CHW | 9-10 | Chicago White Sox | Preseason |
| Mar 25, 2006 | CHW at SF | 7-19 | San Francisco Giants | Preseason |
| Mar 10, 2006 | SF at CHW | 11-6 | San Francisco Giants | Preseason |
| Mar 24, 2005 | CHW at SF | 6-11 | San Francisco Giants | Preseason |
| Mar 7, 2005 | SF at CHW | 6-5 | San Francisco Giants | Preseason |
| Mar 30, 2004 | CHW at SF | 10-3 | Chicago White Sox | Preseason |
| Mar 14, 2004 | SF at CHW | 1-2 | Chicago White Sox | Preseason |
| Jun 12, 2003 | SF at CHW | 8-4 | San Francisco Giants | Regular |
| Jun 11, 2003 | SF at CHW | 11-4 | San Francisco Giants | Regular |
| Jun 10, 2003 | SF at CHW | 3-5 | Chicago White Sox | Regular |
| Mar 3, 2003 | SF at CHW | 1-3 | Chicago White Sox | Preseason |
| Mar 31, 2002 | CHW at SF | 5-2 | Chicago White Sox | Preseason |
| Mar 23, 2002 | CHW at SF | 10-6 | Chicago White Sox | Preseason |
| Mar 19, 2002 | SF at CHW | 11-6 | San Francisco Giants | Preseason |
| Mar 25, 2001 | CHW at SF | 4-2 | Chicago White Sox | Preseason |
| Mar 10, 2001 | SF at CHW | 4-5 | Chicago White Sox | Preseason |
| Mar 23, 2000 | SF at CHW | 7-9 | Chicago White Sox | Preseason |
| Mar 15, 2000 | CHW at SF | 7-8 | San Francisco Giants | Preseason |
| Mar 7, 2000 | CHW at SF | 2-3 | San Francisco Giants | Preseason |
Completed games on file, which start in 2000 — not the clubs’ full all-time series. Regular season 78, postseason 0.