San Francisco 49ers players from USC
16 players
16 players from USC have played for the San Francisco 49ers. Ronnie Lott stayed the longest: 10 seasons. On a roster now: Talanoa Hufanga, Drake Jackson, and Sam Darnold.
| Player | Pos | With club | Seasons |
|---|---|---|---|
| Ronnie Lott | S | 1981–1990 | 10 |
| Tim McDonald | SS | 1993–1999 | 7 |
| Talanoa Hufanga | S | 2021–2024 | 4 |
| Drake Jackson | DE | 2022–2023 | 2 |
| Marcus Martin | C | 2014–2015 | 2 |
| Derrick Deese | OT | 1996–2003 | 2 |
| Sam Darnold | QB | 2023 | 1 |
| Malcolm Smith | LB | 2018 | 1 |
| Reggie Bush | RB | 2015 | 1 |
| Taylor Mays | S | 2010 | 1 |
| Chilo Rachal | OG | 2009 | 1 |
| Johnnie Morton | WR | 2005 | 1 |
| Curtis Conway | WR | 2004 | 1 |
| Frank Strong | DB | 2002 | 1 |
| Matt Keneley | DT | 1999 | 1 |
| Ricky Ervins | RB | 1995 | 1 |
Colleges as ESPN lists them. Seasons are on file in full from 1993; before that only some of the stars are, so an older name can be missing.