San Francisco 49ers players who were first-round picks
92 players
92 first-round picks have played for the San Francisco 49ers. On a roster now: Arik Armstead, Nick Bosa, Brandon Aiyuk, Christian McCaffrey, and Trent Williams.
| Player | Pos | With club | Drafted |
|---|---|---|---|
| Jerry Rice | WR | 1985–2000 | 1985 · No. 16 · SF |
| Bryant Young | DT | 1994–2007 | 1994 · No. 7 · SF |
| Joe Staley | OT | 2007–2019 | 2007 · No. 28 · SF |
| Vernon Davis | TE | 2006–2015 | 2006 · No. 6 · SF |
| Ronnie Lott | S | 1981–1990 | 1981 · No. 8 · SF |
| Arik Armstead | DT | 2015–2023 | 2015 · No. 17 · SF |
| Jimmie Ward | S | 2014–2022 | 2014 · No. 30 · SF |
| Nick Bosa | DE | 2019–2026 | 2019 · No. 2 · SF |
| Patrick Willis | LB | 2007–2014 | 2007 · No. 11 · SF |
| J.J. Stokes | WR | 1995–2002 | 1995 · No. 10 · SF |
| Dana Stubblefield | DT | 1993–2002 | 1993 · No. 26 · SF |
| Dexter Carter | RB | 1990–1996 | 1990 · No. 25 · SF |
| Michael Crabtree | WR | 2009–2014 | 2009 · No. 10 · SF |
| Julian Peterson | LB | 2000–2005 | 2000 · No. 16 · SF |
| Ahmed Plummer | CB | 2000–2005 | 2000 · No. 24 · SF |
| Brandon Aiyuk | WR | 2020–2024 | 2020 · No. 25 · SF |
| Christian McCaffrey | RB | 2022–2026 | 2017 · No. 8 · CAR |
| Eric Reid | S | 2013–2017 | 2013 · No. 18 · SF |
| Trent Williams | OT | 2020–2025 | 2010 · No. 4 · WSH |
| Manny Lawson | LB | 2006–2010 | 2006 · No. 22 · SF |
| Andre Carter | DE | 2001–2005 | 2001 · No. 7 · SF |
| Garrison Hearst | RB | 1997–2003 | 1993 · No. 3 · PHO |
| Javon Kinlaw | DT | 2020–2023 | 2020 · No. 14 · SF |
| Solomon Thomas | DT | 2017–2020 | 2017 · No. 3 · SF |
| DeForest Buckner | DT | 2016–2019 | 2016 · No. 7 · SF |
| Aldon Smith | DE | 2011–2014 | 2011 · No. 7 · SF |
| Mike Iupati | G | 2011–2014 | 2010 · No. 17 · SF |
| Kwame Harris | OT | 2003–2006 | 2003 · No. 26 · SF |
| Mike Rumph | DB | 2002–2005 | 2002 · No. 27 · SF |
| Nate Clements | SS | 2007–2010 | 2001 · No. 21 · BUF |
| William Floyd | FB | 1994–1997 | 1994 · No. 28 · SF |
| Keith DeLong | LB | 1989–1993 | 1989 · No. 28 · SF |
| Mike McGlinchey | OT | 2018–2021 | 2018 · No. 9 · SF |
| Dee Ford | DE | 2019–2021 | 2014 · No. 23 · KC |
| Blaine Gabbert | QB | 2014–2016 | 2011 · No. 10 · JAX |
| Glenn Dorsey | DL | 2013–2016 | 2008 · No. 5 · KC |
| Ted Ginn Jr. | WR | 2010–2012 | 2007 · No. 9 · MIA |
| Donte Whitner | DB | 2011–2013 | 2006 · No. 8 · BUF |
| Carlos Rogers | CB | 2011–2013 | 2005 · No. 9 · WSH |
| Tashaun Gipson Sr. | S | 2022–2024 | 2001 · No. 9 · SEA |
| Takeo Spikes | LB | 2008–2010 | 1998 · No. 13 · CIN |
| Walt Harris | CB | 2006–2008 | 1996 · No. 13 · CHI |
| Dana Hall | DB | 1992–1994 | 1992 · No. 18 · SF |
| Ted Washington | DT | 1991–1993 | 1991 · No. 25 · SF |
| Mike Sherrard | WR | 1990–1992 | 1986 · No. 18 · DAL |
| Chris Doleman | DE | 1996–1998 | 1985 · No. 4 · MIN |
| Ricky Pearsall | WR | 2024–2025 | 2024 · No. 31 · SF |
| Mac Jones | QB | 2025–2026 | 2021 · No. 15 · NE |
| Trey Lance | QB | 2021–2022 | 2021 · No. 3 · SF |
| Clelin Ferrell | DE | 2023–2025 | 2019 · No. 4 · OAK |
| Jason Verrett | CB | 2020–2021 | 2014 · No. 25 · SD |
| Kentwan Balmer | DE | 2008–2009 | 2008 · No. 29 · SF |
| Reggie McGrew | DT | 2000–2001 | 1999 · No. 24 · SF |
| R.W. McQuarters | CB | 1998–1999 | 1998 · No. 28 · SF |
| Jim Druckenmiller | QB | 1997–1998 | 1997 · No. 26 · SF |
| Todd Kelly | DE | 1993–1994 | 1993 · No. 27 · SF |
| Tommy Vardell | FB | 1996–1999 | 1992 · No. 9 · CLE |
| Mykel Williams | DE | 2025 | 2025 · No. 11 · SF |
| Chase Young | DE | 2023 | 2020 · No. 2 · WSH |
| Sam Darnold | QB | 2023 | 2018 · No. 3 · NYJ |
| Leonard Floyd | DE | 2024 | 2016 · No. 9 · CHI |
| Eli Apple | CB | 2025 | 2016 · No. 10 · NYG |
| Darqueze Dennard | CB | 2021 | 2014 · No. 24 · CIN |
| Mike Evans | WR | 2026 | 2014 · No. 7 · TB |
| Datone Jones | DE | 2017 | 2013 · No. 26 · GB |
| Dion Jordan | DE | 2020 | 2013 · No. 3 · MIA |
| Dre Kirkpatrick | CB | 2021 | 2012 · No. 17 · CIN |
| A.J. Jenkins | WR | 2012 | 2012 · No. 30 · SF |
| Jonathan Baldwin | WR | 2013 | 2011 · No. 26 · KC |
| Alex Mack | C | 2021 | 2009 · No. 21 · CLE |
| Leon Hall | CB | 2017 | 2007 · No. 18 · CIN |
| Reggie Bush | RB | 2015 | 2006 · No. 2 · NO |
| Braylon Edwards | WR | 2011 | 2005 · No. 3 · CLE |
| Rashaun Woods | WR | 2004 | 2004 · No. 31 · SF |
| Nnamdi Asomugha | CB | 2013 | 2003 · No. 31 · OAK |
| Bryant Johnson | WR | 2008 | 2003 · No. 17 · ARI |
| Sammy Davis | DB | 2006 | 2003 · No. 30 · SD |
| Ashley Lelie | WR | 2007 | 2002 · No. 19 · DEN |
| David Carr | QB | 2010 | 2002 · No. 1 · HOU |
| Willie Middlebrooks | DB | 2005 | 2001 · No. 24 · DEN |
| Randy Moss | WR | 2012 | 1998 · No. 21 · MIN |
| Lawrence Phillips | RB | 1999 | 1996 · No. 6 · STL |
| Craig Newsome | DB | 1999 | 1995 · No. 32 · GB |
| Antonio Langham | DB | 1998 | 1994 · No. 9 · CLE |
| Johnnie Morton | WR | 2005 | 1994 · No. 21 · DET |
| Trent Dilfer | QB | 2007 | 1994 · No. 6 · TB |
| Curtis Conway | WR | 2004 | 1993 · No. 7 · CHI |
| Irv Smith | TE | 1998 | 1993 · No. 20 · NO |
| Rick Mirer | QB | 2000 | 1993 · No. 2 · SEA |
| Alfred Williams | DE | 1995 | 1991 · No. 18 · CIN |
| Deion Sanders | CB | 1994 | 1989 · No. 5 · ATL |
| Rod Woodson | FS | 1997 | 1987 · No. 10 · PIT |
First-round picks since 1975, drafted by any club. Seasons are on file in full from 1993; before that only some of the stars are, so an older name can be missing.