Buffalo Bills players who were first-round picks
71 players
71 first-round picks have played for the Buffalo Bills. On a roster now: Josh Allen, Ed Oliver, Greg Rousseau, Tremaine Edmunds, and Dalton Kincaid.
| Player | Pos | With club | Drafted |
|---|---|---|---|
| Bruce Smith | DE | 1985–1999 | 1985 · No. 1 · BUF |
| Jim Kelly | QB | 1986–1996 | 1983 · No. 14 · BUF |
| Eric Moulds | WR | 1996–2005 | 1996 · No. 24 · BUF |
| Josh Allen | QB | 2018–2026 | 2018 · No. 7 · BUF |
| Jerry Hughes | DE | 2013–2021 | 2010 · No. 31 · IND |
| Henry Jones | DB | 1992–2000 | 1991 · No. 26 · BUF |
| Cornelius Bennett | LB | 1987–1995 | 1987 · No. 2 · IND |
| Ed Oliver | DT | 2019–2026 | 2019 · No. 9 · BUF |
| Tre'Davious White | CB | 2017–2025 | 2017 · No. 27 · BUF |
| Leodis McKelvin | CB | 2008–2015 | 2008 · No. 11 · BUF |
| Marcell Dareus | DT | 2011–2017 | 2011 · No. 3 · BUF |
| Lee Evans | WR | 2004–2010 | 2004 · No. 13 · BUF |
| Thomas Smith | DB | 1993–1999 | 1993 · No. 28 · BUF |
| Greg Rousseau | LB | 2021–2026 | 2021 · No. 30 · BUF |
| Nate Clements | SS | 2001–2006 | 2001 · No. 21 · BUF |
| Ted Washington | DT | 1995–2000 | 1991 · No. 25 · SF |
| Tremaine Edmunds | LB | 2018–2022 | 2018 · No. 16 · BUF |
| Stephon Gilmore | CB | 2012–2016 | 2012 · No. 10 · BUF |
| C.J. Spiller | RB | 2010–2014 | 2010 · No. 9 · BUF |
| Eric Wood | C | 2012–2017 | 2009 · No. 28 · BUF |
| Donte Whitner | DB | 2006–2010 | 2006 · No. 8 · BUF |
| J.P. Losman | QB | 2004–2008 | 2004 · No. 22 · BUF |
| Antoine Winfield | CB | 1999–2003 | 1999 · No. 23 · BUF |
| Shane Conlan | LB | 1987–1992 | 1987 · No. 8 · BUF |
| Dalton Kincaid | TE | 2023–2026 | 2023 · No. 25 · BUF |
| EJ Manuel | QB | 2013–2016 | 2013 · No. 16 · BUF |
| Marshawn Lynch | RB | 2007–2010 | 2007 · No. 12 · BUF |
| John McCargo | DT | 2006–2010 | 2006 · No. 26 · BUF |
| Mario Williams | DE | 2012–2015 | 2006 · No. 1 · HOU |
| Takeo Spikes | LB | 2003–2006 | 1998 · No. 13 · CIN |
| Antowain Smith | RB | 1997–2000 | 1997 · No. 23 · BUF |
| Jeff Burris | CB | 1994–1997 | 1994 · No. 27 · BUF |
| John Fina | OT | 1992–1996 | 1992 · No. 27 · BUF |
| Ronnie Harmon | RB | 1986–1989 | 1986 · No. 16 · BUF |
| James Lofton | WR | 1989–1992 | 1978 · No. 6 · GB |
| Kaiir Elam | CB | 2022–2024 | 2022 · No. 23 · BUF |
| Mitchell Trubisky | QB | 2021–2025 | 2017 · No. 2 · CHI |
| Sammy Watkins | WR | 2014–2016 | 2014 · No. 4 · BUF |
| Star Lotulelei | DT | 2018–2021 | 2013 · No. 14 · CAR |
| Von Miller | LB | 2022–2024 | 2011 · No. 2 · DEN |
| Manny Lawson | LB | 2013–2015 | 2006 · No. 22 · SF |
| Willis McGahee | RB | 2004–2006 | 2003 · No. 23 · BUF |
| Marcus Stroud | DT | 2008–2010 | 2001 · No. 13 · JAX |
| Sam Adams | DT | 2003–2005 | 1994 · No. 8 · SEA |
| Drew Bledsoe | QB | 2002–2004 | 1993 · No. 1 · NE |
| Troy Vincent | DB | 2004–2006 | 1992 · No. 7 · MIA |
| Jim Jeffcoat | DE | 1995–1997 | 1983 · No. 23 · DAL |
| Maxwell Hairston | CB | 2025–2026 | 2025 · No. 30 · BUF |
| Kelvin Benjamin | WR | 2017–2018 | 2014 · No. 28 · CAR |
| Percy Harvin | WR | 2015–2016 | 2009 · No. 22 · MIN |
| Aaron Maybin | LB | 2009–2010 | 2009 · No. 11 · BUF |
| Shawne Merriman | DE | 2011–2012 | 2005 · No. 12 · SD |
| Nick Barnett | LB | 2011–2012 | 2003 · No. 29 · GB |
| Erik Flowers | DE | 2000–2001 | 2000 · No. 26 · BUF |
| Ruben Brown | OG | 2001–2002 | 1995 · No. 14 · BUF |
| Darnell Savage | S | 2025 | 2019 · No. 21 · GB |
| DJ Moore | WR | 2026 | 2018 · No. 24 · CAR |
| Bradley Chubb | LB | 2026 | 2018 · No. 5 · DEN |
| Leonard Fournette | RB | 2023 | 2017 · No. 4 · JAX |
| Joey Bosa | DE | 2025 | 2016 · No. 3 · SD |
| Leonard Floyd | DE | 2023 | 2016 · No. 9 · CHI |
| Amari Cooper | WR | 2024 | 2015 · No. 4 · OAK |
| Shaq Thompson | LB | 2025 | 2015 · No. 25 · CAR |
| Brandin Cooks | WR | 2025 | 2014 · No. 20 · NO |
| Xavier Rhodes | CB | 2022 | 2013 · No. 25 · MIN |
| Corey Liuget | DT | 2019 | 2011 · No. 18 · SD |
| Kareem Jackson | S | 2024 | 2010 · No. 20 · HOU |
| Vontae Davis | CB | 2018 | 2009 · No. 25 · MIA |
| Keith Rivers | LB | 2014 | 2008 · No. 9 · CIN |
| Reggie Bush | RB | 2016 | 2006 · No. 2 · NO |
| Wayne Simmons | LB | 1998 | 1993 · No. 15 · GB |
First-round picks since 1975, drafted by any club. Seasons are on file in full from 1993; before that only some of the stars are, so an older name can be missing.