San Francisco 49ers vs Tennessee Titans head-to-head
Who has won more, the San Francisco 49ers or the Tennessee Titans?
San Francisco 49ers lead the series 11-8 in 19 meetings since Nov 15, 1970. They average 21.3 to 19.8. The last meeting was Aug 13, 2026, 19-13.
- Record
- San Francisco 49ers 11-8 Tennessee Titans
- Games
- 19
- Points per game
- 21.3 – 19.8
- Biggest win
- San Francisco 49ers by 22
Every meeting on file
| Aug 13, 2026 |  TEN at  SF | 19-13 | Tennessee Titans | Preseason |
| Dec 14, 2025 | TEN at SF | 24-37 | San Francisco 49ers | Regular |
| Aug 10, 2024 | SF at TEN | 13-17 | Tennessee Titans | Preseason |
| Dec 23, 2021 | SF at TEN | 17-20 | Tennessee Titans | Regular |
| Dec 17, 2017 | TEN at SF | 23-25 | San Francisco 49ers | Regular |
| Oct 20, 2013 | SF at TEN | 31-17 | San Francisco 49ers | Regular |
| Nov 8, 2009 | TEN at SF | 34-27 | Tennessee Titans | Regular |
| Nov 27, 2005 | SF at TEN | 22-33 | Tennessee Titans | Regular |
| Aug 26, 2005 | TEN at SF | 13-16 | San Francisco 49ers | Preseason |
| Oct 3, 1999 | TEN at SF | 22-24 | San Francisco 49ers | Regular |
| Oct 27, 1996 | SF at TEN | 10-9 | San Francisco 49ers | Regular |
| Dec 25, 1993 | TEN at SF | 10-7 | Tennessee Titans | Regular |
| Oct 7, 1990 | SF at TEN | 24-21 | San Francisco 49ers | Regular |
| Nov 8, 1987 | TEN at SF | 20-27 | San Francisco 49ers | Regular |
| Oct 21, 1984 | SF at TEN | 34-21 | San Francisco 49ers | Regular |
| Dec 13, 1981 | TEN at SF | 6-28 | San Francisco 49ers | Regular |
| Sep 17, 1978 | SF at TEN | 7-20 | Tennessee Titans | Regular |
| Dec 7, 1975 | TEN at SF | 27-13 | Tennessee Titans | Regular |
| Nov 15, 1970 | SF at TEN | 30-20 | San Francisco 49ers | Regular |
Completed games on file, which start in 1970 — not the clubs’ full all-time series. Regular season 19, postseason 0.