Buffalo Bills vs Carolina Panthers head-to-head
Who has won more, the Buffalo Bills or the Carolina Panthers?
Buffalo Bills lead the series 10-7 in 17 meetings since Sep 10, 1995. They average 22.1 to 17.0. The last meeting was Aug 15, 2026, 29-14.
- Record
- Buffalo Bills 10-7 Carolina Panthers
- Games
- 17
- Points per game
- 22.1 – 17.0
- Biggest win
- Buffalo Bills by 31
Buffalo Bills have won the last 2 meetings.
Every meeting on file
| Aug 15, 2026 |  CAR at  BUF | 14-29 | Buffalo Bills | Preseason |
| Oct 26, 2025 | BUF at CAR | 40-9 | Buffalo Bills | Regular |
| Aug 24, 2024 | CAR at BUF | 31-26 | Carolina Panthers | Preseason |
| Aug 26, 2022 | BUF at CAR | 0-21 | Carolina Panthers | Preseason |
| Dec 19, 2021 | CAR at BUF | 14-31 | Buffalo Bills | Regular |
| Aug 16, 2019 | BUF at CAR | 27-14 | Buffalo Bills | Preseason |
| Aug 9, 2018 | CAR at BUF | 28-23 | Carolina Panthers | Preseason |
| Sep 17, 2017 | BUF at CAR | 3-9 | Carolina Panthers | Regular |
| Aug 14, 2015 | CAR at BUF | 25-24 | Carolina Panthers | Preseason |
| Aug 8, 2014 | BUF at CAR | 20-18 | Buffalo Bills | Preseason |
| Sep 15, 2013 | CAR at BUF | 23-24 | Buffalo Bills | Regular |
| Oct 25, 2009 | BUF at CAR | 20-9 | Buffalo Bills | Regular |
| Aug 12, 2006 | BUF at CAR | 13-14 | Carolina Panthers | Preseason |
| Nov 27, 2005 | CAR at BUF | 13-9 | Carolina Panthers | Regular |
| Dec 9, 2001 | CAR at BUF | 24-25 | Buffalo Bills | Regular |
| Oct 25, 1998 | BUF at CAR | 30-14 | Buffalo Bills | Regular |
| Sep 10, 1995 | CAR at BUF | 9-31 | Buffalo Bills | Regular |
Completed games on file, which start in 1995 — not the clubs’ full all-time series. Regular season 17, postseason 0.