Arizona Cardinals vs Buffalo Bills head-to-head
Who has won more, the Arizona Cardinals or the Buffalo Bills?
Buffalo Bills lead the series 9-5 in 14 meetings since Oct 31, 1971. They average 22.2 to 25.6. The last meeting was Sep 8, 2024, 34-28.
- Record
- Arizona Cardinals 5-9 Buffalo Bills
- Games
- 14
- Points per game
- 22.2 – 25.6
- Biggest win
- Buffalo Bills by 31
Every meeting on file
| Sep 8, 2024 |  ARI at  BUF | 28-34 | Buffalo Bills | Regular |
| Nov 15, 2020 | BUF at ARI | 30-32 | Arizona Cardinals | Regular |
| Sep 25, 2016 | ARI at BUF | 18-33 | Buffalo Bills | Regular |
| Oct 14, 2012 | BUF at ARI | 19-16 | Buffalo Bills | Regular |
| Oct 5, 2008 | BUF at ARI | 17-41 | Arizona Cardinals | Regular |
| Oct 31, 2004 | ARI at BUF | 14-38 | Buffalo Bills | Regular |
| Dec 19, 1999 | BUF at ARI | 31-21 | Buffalo Bills | Regular |
| Nov 11, 1990 | ARI at BUF | 14-45 | Buffalo Bills | Regular |
| Sep 21, 1986 | ARI at BUF | 10-17 | Buffalo Bills | Regular |
| Sep 9, 1984 | BUF at ARI | 7-37 | Arizona Cardinals | Regular |
| Nov 15, 1981 | BUF at ARI | 0-24 | Arizona Cardinals | Regular |
| Nov 27, 1975 | ARI at BUF | 14-32 | Buffalo Bills | Regular |
| Nov 27, 1975 | BUF at ARI | 32-14 | Buffalo Bills | Regular |
| Oct 31, 1971 | ARI at BUF | 28-23 | Arizona Cardinals | Regular |
Completed games on file, which start in 1971 — not the clubs’ full all-time series. Regular season 14, postseason 0.