Fighting Irish 42, Panthers 21
Final · ABC · Acrisure Stadium
| Team | 1 | 2 | 3 | 4 | T |
|---|---|---|---|---|---|
 ND | 7 | 28 | 7 | 0 | 42 |
 PITT | 10 | 3 | 0 | 8 | 21 |
The Notre Dame Fighting Irish beat the Pittsburgh Panthers 42-21 on Sep 3, 2005 at Acrisure Stadium.
Top performers
Brady Quinn threw for 227 yards, 2 touchdowns and 1 interception for the Fighting Irish.
Darius Walker ran for 100 yards on 20 carries.
Tyler Palko threw for 220 yards, 1 touchdown and 1 interception for the Panthers.
Raymond Kirkley Jr. ran for 64 yards on 5 carries.
Before and after
- Fighting Irish · 2005 season · Next Sep 10, 2005: ND 17, MICH 10
- Panthers · 2005 season · Next Sep 9, 2005: PITT 10, OHIO 16
Other Fighting Irish vs Panthers games
| Nov 15, 2025 | ND at PITT | 37-15 | Regular |
| Oct 28, 2023 | PITT at ND | 7-58 | Regular |
| Oct 24, 2020 | ND at PITT | 45-3 | Regular |
| Oct 13, 2018 | PITT at ND | 14-19 | Regular |
| Nov 7, 2015 | ND at PITT | 42-30 | Regular |
| Nov 9, 2013 | ND at PITT | 21-28 | Regular |